Fragrance material review on 4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one

Food Chem Toxicol. 2007:45 Suppl 1:S232-4. doi: 10.1016/j.fct.2007.09.014. Epub 2007 Sep 14.

Authors

J Lalko¹, A Lapczynski, D McGinty, S Bhatia, C S Letizia, A M Api

Affiliation

¹ Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA.

PMID: 18023516
DOI: 10.1016/j.fct.2007.09.014

Abstract

A toxicologic and dermatologic review of 4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one when used as a fragrance ingredient is presented.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Butanes / classification
Butanes / pharmacokinetics
Butanes / toxicity*
Consumer Product Safety
Cyclohexanes / classification
Cyclohexanes / pharmacokinetics
Cyclohexanes / toxicity*
Dose-Response Relationship, Drug
Humans
Mutagenicity Tests
Mutagens / classification
Mutagens / pharmacokinetics
Mutagens / toxicity*
Perfume / classification
Perfume / pharmacokinetics
Perfume / toxicity*
Risk Assessment
Salmonella typhimurium / drug effects
Salmonella typhimurium / genetics
Skin / drug effects
Skin / metabolism
Skin Absorption

Substances

4-(1,2-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one
Butanes
Cyclohexanes
Mutagens
Perfume