Synthesis and properties of DNA duplexes containing cytosine analogs carrying phosphodiester functions

A T M Zafrul Azam; Itaru Okamoto; Akira Ono

doi:10.1093/nass/nrm077

Synthesis and properties of DNA duplexes containing cytosine analogs carrying phosphodiester functions

Nucleic Acids Symp Ser (Oxf). 2007:(51):153-4. doi: 10.1093/nass/nrm077.

Authors

A T M Zafrul Azam¹, Itaru Okamoto, Akira Ono

Affiliation

¹ Department of Material and Life Chemistry, Faculty of Engineering, Kanagawa University, 3-27-1 Rokkakubashi, Kanagawa-ku, Yokohama, Kanagawa 221-8686, Japan.

PMID: 18029632
DOI: 10.1093/nass/nrm077

Abstract

DNA duplexes containing cytosine residues bearing a phosphodiester function (X) were synthesized. The stability of the duplexes was investigated by UV-melting experiments.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cytosine / analogs & derivatives*
Cytosine / chemistry
DNA / chemical synthesis*
DNA / chemistry
Nucleic Acid Denaturation
Organophosphates / chemistry*
Temperature

Substances

4-N-hydroxyethyl-2'-deoxycytosine methyl phosphate diester
Organophosphates
Cytosine
DNA