Unimolecular decomposition of M+. and [M+H]+ species of some fluorosubstituted acyclic nucleoside analogs

Rapid Commun Mass Spectrom. 1991 Feb;5(2):72-7. doi: 10.1002/rcm.1290050206.

Abstract

Electron ionization and fast-atom bombardment mass spectrometry are shown to provide a valid analytical tool for the structural characterization of the title compounds. In fact, diagnostic fragmentation pathways were observed depending on the presence of different substituents (benzyloxy, (benzyloxy, p-tolylthio, p-tolylsulphinyl) as well as of different bases. Regioisomeric compounds could be differentiated by kinetic energy release measurements.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Mass Spectrometry / methods
  • Nucleosides / chemistry*
  • Spectrometry, Mass, Fast Atom Bombardment

Substances

  • Nucleosides