Abstract
Three glycolipids (1--3), possessing a sugar moiety at C-2 of glycerol ether, have been isolated from the Formosan soft coral Lobophytum crassum. Their structures were elucidated by spectroscopic methods, particularly in 1D- and 2D-NMR experiments. The absolute configurations on the sugar portion and lipid aglycon of 1--3 were determined by methanolysis, chemical transformation and the application of Mosher's method on 1 and 3. Compounds 1--3 exhibited weak cytotoxic activities.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anthozoa / chemistry*
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / isolation & purification
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Antineoplastic Agents / pharmacology
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Cell Line, Tumor
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Chromatography, Thin Layer
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Drug Screening Assays, Antitumor
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Glycolipids / chemistry*
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Glycolipids / isolation & purification
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Glycolipids / pharmacology
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Humans
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Hydrolysis
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Indicators and Reagents
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Mass Spectrometry
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Taiwan
Substances
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Antineoplastic Agents
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Glycolipids
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Indicators and Reagents