[Differences between the neuropsychological profiles of Asperger's syndrome and non-verbal learning disorder]

Rev Neurol. 2007 Dec;45(12):713-9.
[Article in Spanish]

Abstract

Introduction: The validity of the Asperger syndrome (AS) diagnose continues to be debated due to the lack of consensus on its definition, specially regarding higher-functioning autism. Previous research has suggested that the neuropsychological profile of the non verbal learning syndrome (NVLS) might be utilized to sustain a differential diagnose of the AS with other diseases associated with development.

Aim: To analyze the neuropsychological profile of children diagnosed with AS and compare with those obtained from children with NVLS.

Subjects and methods: All cognitive domains from 15 children have been evaluated with an extensive variety of tests; 5 were diagnosed with AS and 5 with NVLS, all of them submitted to the Nino Jesus Children's University Hospital. As a control group, another 5 children with no pathology were evaluated.

Results: Obtained data shows significant differences between the two groups under study. Profile from individuals under AS shows deficit in linguistic as well as non verbal skills and, when compared to the control group, executive functions seem to be generally more altered.

Conclusions: Further investigation is suggested to determine that the NVLS could be an explanation model for AS. On the other hand, we stress the need to deepen the study of the executive functions and their relationship with the mind's theory, as an hypothesis to explain the AS.

Publication types

  • Comparative Study

MeSH terms

  • Asperger Syndrome / diagnosis
  • Asperger Syndrome / physiopathology
  • Asperger Syndrome / psychology*
  • Birth Injuries / complications
  • Brain Neoplasms / complications
  • Brain Neoplasms / therapy
  • Cerebellar Neoplasms / complications
  • Cerebellar Neoplasms / therapy
  • Child
  • Cohort Studies
  • Diagnosis, Differential
  • Ependymoma / complications
  • Ependymoma / therapy
  • Female
  • Humans
  • Learning Disabilities / diagnosis
  • Learning Disabilities / etiology
  • Learning Disabilities / physiopathology
  • Learning Disabilities / psychology*
  • Male
  • Medulloblastoma / complications
  • Medulloblastoma / therapy
  • Models, Psychological
  • Neuropsychological Tests*
  • Nonverbal Communication
  • Psychomotor Performance
  • Risk Factors
  • Social Perception
  • Stroke / complications