Classifying CT image data into material fractions by a scale and rotation invariant edge model

IEEE Trans Image Process. 2007 Dec;16(12):2891-904. doi: 10.1109/tip.2007.909407.

Abstract

A fully automated method is presented to classify 3-D CT data into material fractions. An analytical scale-invariant description relating the data value to derivatives around Gaussian blurred step edges--arch model--is applied to uniquely combine robustness to noise, global signal fluctuations, anisotropic scale, noncubic voxels, and ease of use via a straightforward segmentation of 3-D CT images through material fractions. Projection of noisy data value and derivatives onto the arch yields a robust alternative to the standard computed Gaussian derivatives. This results in a superior precision of the method. The arch-model parameters are derived from a small, but over-determined, set of measurements (data values and derivatives) along a path following the gradient uphill and downhill starting at an edge voxel. The model is first used to identify the expected values of the two pure materials (named L and H) and thereby classify the boundary. Second, the model is used to approximate the underlying noise-free material fractions for each noisy measurement. An iso-surface of constant material fraction accurately delineates the material boundary in the presence of noise and global signal fluctuations. This approach enables straightforward segmentation of 3-D CT images into objects of interest for computer-aided diagnosis and offers an easy tool for the design of otherwise complicated transfer functions in high-quality visualizations. The method is applied to segment a tooth volume for visualization and digital cleansing for virtual colonoscopy.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Artificial Intelligence*
  • Imaging, Three-Dimensional / methods*
  • Pattern Recognition, Automated / methods*
  • Radiographic Image Enhancement / methods
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Reproducibility of Results
  • Rotation
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / methods*