Out FOXing Parkinson disease: where development meets neurodegeneration

PLoS Biol. 2007 Dec;5(12):e334. doi: 10.1371/journal.pbio.0050334.

Abstract

The central survival role of FOX proteins may allow a unified view of the genetic and environmental factors that cause Parkinson disease.

MeSH terms

  • Aging / physiology
  • Animals
  • Disease Models, Animal
  • Forkhead Transcription Factors / genetics
  • Forkhead Transcription Factors / metabolism*
  • Humans
  • Nerve Degeneration / genetics
  • Nerve Degeneration / metabolism*
  • Nerve Degeneration / pathology*
  • Parkinson Disease / genetics
  • Parkinson Disease / metabolism*
  • Parkinson Disease / pathology*

Substances

  • Forkhead Transcription Factors