[A case of therapy-related acute myeloid leukemia associated with inv(16)]

So-Young Lee; Myungshin Kim; Jihyang Lim; Yonggoo Kim; Kyungja Han; Sung Yong Kim; Hee Je Kim; In-Yang Park

doi:10.3343/kjlm.2007.27.1.19

[A case of therapy-related acute myeloid leukemia associated with inv(16)]

Korean J Lab Med. 2007 Feb;27(1):19-21. doi: 10.3343/kjlm.2007.27.1.19.

[Article in Korean]

Authors

So-Young Lee¹, Myungshin Kim, Jihyang Lim, Yonggoo Kim, Kyungja Han, Sung Yong Kim, Hee Je Kim, In-Yang Park

Affiliation

¹ Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

PMID: 18094545
DOI: 10.3343/kjlm.2007.27.1.19

Abstract

The inv(16)(p13q22) is found in de novo AML and is closely associated with the FAB subtype M4eo. The inv(16) is rarely reported in therapy-related AML (t-AML) patients. Herein, we report a case of t-AML with inv(16) after combination chemotherapy using antimitotic agent and alkylating agent (cis-platin-paclitaxel) for ovarian serous cystadenocarcinoma.

Publication types

Case Reports

MeSH terms

Antimitotic Agents / adverse effects*
Antimitotic Agents / therapeutic use
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Chromosome Inversion*
Chromosomes, Human, Pair 16 / genetics*
Cisplatin / adverse effects
Cisplatin / therapeutic use
Female
Humans
Leukemia, Myeloid, Acute / chemically induced*
Leukemia, Myeloid, Acute / pathology
Middle Aged
Paclitaxel
Taxoids / adverse effects
Taxoids / therapeutic use

Substances

Antimitotic Agents
Taxoids
Paclitaxel
Cisplatin

Supplementary concepts

TP protocol