Cardiac re-synchronization therapy in a child with severe anthracycline-induced congestive heart failure and normal QRS duration

J Heart Lung Transplant. 2007 Dec;26(12):1333-5. doi: 10.1016/j.healun.2007.09.003. Epub 2007 Nov 26.

Abstract

We report the case of a 9-year-old girl who developed acute anthracycline-induced cardiotoxicity with severe, refractory congestive heart failure. Rescue treatment with cardiac re-synchronization therapy was initiated, resulting in rapid improvement in left ventricular function and clinical status.

Publication types

  • Case Reports

MeSH terms

  • Anthracyclines / adverse effects*
  • Anthracyclines / therapeutic use
  • Child
  • Electrocardiography*
  • Female
  • Heart Failure / chemically induced*
  • Heart Failure / physiopathology
  • Heart Failure / therapy*
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy
  • Pacemaker, Artificial*
  • Stroke Volume / physiology
  • Ultrasonography
  • Ventricular Dysfunction, Left / diagnostic imaging
  • Ventricular Dysfunction, Left / physiopathology

Substances

  • Anthracyclines