Perioperative events during deep brain stimulation: the experience at cleveland clinic

J Neurosurg Anesthesiol. 2008 Jan;20(1):36-40. doi: 10.1097/ANA.0b013e318157a15a.

Abstract

Background: Deep brain stimulation (DBS) of the basal ganglia is an evolving technique for managing intractable movement disorders such as those due to Parkinson disease. We conducted a retrospective review of the DBS procedures that have been performed at our institution to determine the frequency and types complications that occurred.

Methods: After Institutional Review Board approval, 258 procedures involving 250 patients were retrospectively reviewed. Univariate analysis using the chi test for the categorical variables and a t-test for the continuous variables was performed on patients with and without complications to determine potential risk factors.

Results: The most common anesthesia technique used for DBS procedures was monitored anesthesia care using a propofol infusion during the early part of the case. Airway, respiratory, neurologic, and psychologic/psychiatric complications occurred. Age was found to be an independent risk factor for complications during DBS.

Conclusion: This retrospective study demonstrates that age is an independent risk factor for complications during DBS procedures. Monitored anesthesia care using propofol seems to be a safe technique for DBS procedures; however, dexmedetomidine can also be used.

MeSH terms

  • Age Factors
  • Aged
  • Analysis of Variance
  • Anesthesia, Intravenous
  • Anesthetics, Intravenous
  • Deep Brain Stimulation / adverse effects*
  • Dexmedetomidine
  • Electrodes, Implanted / adverse effects*
  • Female
  • Humans
  • Hypnotics and Sedatives
  • Intraoperative Complications / epidemiology
  • Male
  • Middle Aged
  • Neurosurgical Procedures / adverse effects*
  • Postoperative Complications / epidemiology
  • Propofol
  • Prosthesis Implantation / adverse effects*
  • Retrospective Studies
  • Risk Factors

Substances

  • Anesthetics, Intravenous
  • Hypnotics and Sedatives
  • Dexmedetomidine
  • Propofol