The current prospective, randomized, controlled study aimed to assess the clinical efficacy of the perifollicular vascularity assessment by using power Doppler ultrasonography, as an additive criterion to the standard morphologic ones, for choosing the most competent oocytes. Data obtained from 60 infertile patients who were >40 years of age and were unselected for ovarian reserve showed that this approach does not improve any reproductive outcomes in IVF programs.