Indeno[1,2-d]pyrido[1,2-a]pyrimidines: a new class of receptor tyrosine kinase inhibitors

ChemMedChem. 2008 Mar;3(3):429-33. doi: 10.1002/cmdc.200700306.

Authors

Maria Tsanakopoulou¹, Thomas Cottin, Anita Büttner, Vasiliki Sarli, Elizabeth Malamidou-Xenikaki, Spyros Spyroudis, Athanassios Giannis

Affiliation

¹ Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

PMID: 18181120
DOI: 10.1002/cmdc.200700306

No abstract available

MeSH terms

Adenosine Triphosphate / metabolism
Antineoplastic Agents / chemical synthesis
Antineoplastic Agents / pharmacology*
Cell Membrane Permeability / drug effects*
Cell Membrane Permeability / physiology
Cell Proliferation / drug effects*
Cells, Cultured
Humans
Indenes / pharmacology*
Inhibitory Concentration 50
Protein Kinase Inhibitors / chemical synthesis
Protein Kinase Inhibitors / pharmacology*
Pyrimidines / pharmacology*
Receptor Protein-Tyrosine Kinases / antagonists & inhibitors*
Spectrum Analysis
Umbilical Cord / cytology
Umbilical Cord / drug effects*
Umbilical Cord / metabolism

Substances

Antineoplastic Agents
Indenes
Protein Kinase Inhibitors
Pyrimidines
Adenosine Triphosphate
Receptor Protein-Tyrosine Kinases