Tetanus in an injecting buprenorphine abuser

Ann Acad Med Singap. 2007 Dec;36(12):1021-3.

Abstract

Introduction: Injecting drug abusers are vulnerable to many infectious complications. We describe a case of tetanus in a Singaporean who regularly abused buprenorphine.

Clinical picture: A 49-year-old male was hospitalised for progressive generalised spasms associated with dysarthria and opisthotonus. Tetanus was diagnosed clinically.

Treatment: Supportive management was instituted in the intensive care unit (ICU). Toxicology samples tested positive for buprenorphine.

Outcome: He recovered rapidly and was transferred out of the ICU after 8 days. Retrospective questioning confirmed parenteral abuse of buprenorphine.

Conclusion: This case highlights an uncommon and potentially lethal complication of parenteral drug abuse.

Publication types

  • Case Reports

MeSH terms

  • Buprenorphine*
  • Disease Progression
  • Dysarthria
  • Humans
  • Male
  • Middle Aged
  • Singapore
  • Substance Abuse, Intravenous
  • Substance-Related Disorders / complications*
  • Tetanus / diagnosis
  • Tetanus / etiology*
  • Tetanus / therapy

Substances

  • Buprenorphine