Case reports: minocycline-induced hyperpigmentation resolves during oral isotretinoin therapy

Jennifer Soung; Justine Cohen; Robert Phelps; Steven R Cohen

Case reports: minocycline-induced hyperpigmentation resolves during oral isotretinoin therapy

J Drugs Dermatol. 2007 Dec;6(12):1232-6.

Authors

Jennifer Soung¹, Justine Cohen, Robert Phelps, Steven R Cohen

Affiliation

¹ Department of Dermatology, Mount Sinai School of Medicine, New York, NY, USA.

PMID: 18189065

Abstract

Although disfiguring hyperpigmentation is a well-defined complication of minocycline therapy, modalities to reverse the phenomenon are unpredictable. We report a case of minocycline-induced, blue-black pigmentation in a 23-year-old Hispanic man, which resolved after treatment with oral isotretinoin for acne vulgaris.

Publication types

Case Reports

MeSH terms

Acne Vulgaris / drug therapy
Adult
Anti-Bacterial Agents / adverse effects*
Dermatologic Agents / therapeutic use*
Humans
Hyperpigmentation / chemically induced
Hyperpigmentation / drug therapy*
Hyperpigmentation / pathology
Isotretinoin / therapeutic use*
Male
Minocycline / adverse effects*
Skin / pathology

Substances

Anti-Bacterial Agents
Dermatologic Agents
Isotretinoin
Minocycline