Abstract
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has not been recognised previously as a cause of MRSA infections in Spain. Nineteen patients carrying Panton-Valentine leukocidin (PVL)-positive MRSA were identified in a Barcelona hospital, of whom 15 were immigrants, mostly from South America. Twelve developed skin and soft-tissue infections. The associated isolates carried the PVL gene and staphylococcal chromosomal cassette (SCC)mecIV. A dominant clone belonging to sequence type (ST)8 and related to the USA300 clone was identified by pulsed-field gel electrophoresis. This clone is emerging in Spain, primarily among immigrants from South America, but dissemination to the native Spanish population could increase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Bacterial Toxins / genetics
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Child
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Communicable Diseases, Emerging / epidemiology*
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Communicable Diseases, Emerging / microbiology
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Community-Acquired Infections / epidemiology*
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Community-Acquired Infections / microbiology
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Emigration and Immigration
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Exotoxins / genetics
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Female
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Humans
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Leukocidins / genetics
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Male
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Methicillin Resistance*
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Middle Aged
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Soft Tissue Infections / epidemiology
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Soft Tissue Infections / microbiology
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Spain / epidemiology
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Staphylococcal Infections / epidemiology*
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Staphylococcal Infections / microbiology
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Staphylococcal Skin Infections / epidemiology
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Staphylococcus aureus / drug effects*
Substances
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Bacterial Toxins
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Exotoxins
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Leukocidins
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Panton-Valentine leukocidin