[Sentinel lymph node biopsy under local anaesthesia: how to avoid the disadvantages of intraoperative examination?]

Gynecol Obstet Fertil. 2008 Jan;36(1):79-84. doi: 10.1016/j.gyobfe.2007.09.020. Epub 2008 Jan 10.
[Article in French]

Abstract

The sentinel lymph node procedure has become the standard in the surgical management of localised breast cancer. However, it is submitted to the uncertainties of intraoperative examination. Indeed, intraoperative examination has three major disadvantages: the type of histological method (frozen section versus imprint cytology), the size of sentinel node metastasis (macro- versus micrometastases) and the time requested for this technique. All of these limits are responsible for secondary re-interventions to complete axillary lymph node dissection. Few medical teams have described a new surgical strategy to avoid these limits. They proposed the detection of the sentinel lymph node under local anaesthesia and to wait for the definitive histological analysis before carrying out lumpectomy and axillary lymphadenectomy if necessary under general anaesthesia. We realized a review of the literature on this new procedure to evaluate its feasibility and to assess the technical aspects.

Publication types

  • English Abstract

MeSH terms

  • Anesthesia, Local*
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery*
  • Female
  • Humans
  • Intraoperative Care
  • Intraoperative Period
  • Lymph Node Excision
  • Neoplasm Staging
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Sentinel Lymph Node Biopsy / methods*
  • Sentinel Lymph Node Biopsy / standards