Psychiatric comorbidity in young cocaine users: induced versus independent disorders

Addiction. 2008 Feb;103(2):284-93. doi: 10.1111/j.1360-0443.2007.02076.x.

Abstract

Aims: To examine the psychiatric status of young cocaine users using a validated instrument for the evaluation of psychiatric comorbidity, emphasizing the distinction between independent and induced psychiatric conditions.

Design: Cross-sectional study.

Setting: Barcelona, Spain.

Participants: A cohort of 139 young (18-30 years) adult current regular cocaine users.

Measurements: The Psychiatric Research Interview for Substance and Mental Disorders (PRISM-IV, which produces diagnoses according to DSM-IV criteria, including Axis II antisocial and borderline personality disorders).

Findings: Nearly 42.5% of the subjects presented psychiatric comorbidity. The most common Axis I diagnoses were mood disorders (26.6%) and anxiety disorders (13%). Increasing age, having ever received treatment for drug use and freebase cocaine use were associated with substance-induced disorders diagnoses relative to primary Axis I disorders.

Conclusions: This study has shown a relatively high prevalence of psychiatric comorbidity in cocaine users recruited in non-clinical settings. Future studies examining potential differential factors associated with primary versus substance-induced disorders are necessary to optimize the implementation of more suitable approaching programmes for young regular cocaine users.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Cocaine-Related Disorders / epidemiology*
  • Cocaine-Related Disorders / psychology
  • Crack Cocaine / adverse effects
  • Dopamine Uptake Inhibitors / adverse effects*
  • Epidemiologic Methods
  • Female
  • Humans
  • Male
  • Mental Disorders / chemically induced
  • Mental Disorders / epidemiology*
  • Psychiatric Status Rating Scales
  • Spain / epidemiology

Substances

  • Crack Cocaine
  • Dopamine Uptake Inhibitors