HIV-1 hides an Achilles' heel in virion lipids

Immunity. 2008 Jan;28(1):10-2. doi: 10.1016/j.immuni.2007.12.005.

Abstract

In this issue, Sun et al. (2008) model the interface between a neutralizing antibody and HIV-1 glycoprotein 41 (gp41) envelope peptide in lipids. This model could help overcome a roadblock in HIV-1 vaccine development.

Publication types

  • Comment

MeSH terms

  • Animals
  • HIV-1 / immunology*
  • HIV-1 / metabolism
  • Humans
  • Lipids / immunology*
  • Virion / immunology*
  • Virion / metabolism

Substances

  • Lipids