The aim of the case report was to describe gingival enlargement in a patient who came to the Department of Oral Medicine and Periodontology at Nis Dental Clinic. After anamnesis had been taken, and following clinical examination, laboratory blood analysis, radiological examination and pathological examination, it was established that gingival enlargement was a consequence of medicament injection. We are of the opinion that gingival enlargement was a consequence of sclerotic agent injection.