[Effects of intratumoral injection therapy of dendritic cells combined with hyperthermia for cancer patients]

Gan To Kagaku Ryoho. 2007 Nov;34(12):1905-7.
[Article in Japanese]

Abstract

We proceeded with intratumoral injection therapy of dendritic cells (DC) in combination with hyperthermia for 41 cancer patients in the past two years. We confirmed a total of two CR cases (one of them already reported). We report two successful cases in this paper. Case 1: A uterine cervical cancer patient with metastases in cervical and abdominal lymphnodes was treated with intratumoral DC injection therapy combined with hyperthermia in cervical. She showed a CR not only in cervical but also in abdominal lymph nodes. Case 2: A sialyl grand cancer patient with metastases in cervical and axillary lymphnodes was treated with intratumoral DC injection therapy combined with hyperthermia in cervical. She showed a PR.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Carcinoembryonic Antigen / blood
  • Dendritic Cells / immunology*
  • Dendritic Cells / transplantation*
  • Female
  • Humans
  • Hyperthermia, Induced*
  • Immunotherapy
  • Injections, Intralesional
  • Lymphatic Metastasis / immunology
  • Lymphatic Metastasis / pathology
  • Middle Aged
  • Positron-Emission Tomography
  • Salivary Gland Neoplasms / immunology*
  • Salivary Gland Neoplasms / pathology
  • Salivary Gland Neoplasms / therapy*
  • Tomography, X-Ray Computed
  • Uterine Cervical Neoplasms / immunology*
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / therapy*

Substances

  • Carcinoembryonic Antigen