Chronic pancreatitis: a sequela of acute fatty liver of pregnancy

Hepatobiliary Pancreat Dis Int. 2008 Feb;7(1):101-4.

Abstract

Background: Chronic pancreatitis following acute fatty liver of pregnancy is rarely reported.

Methods: We treated a 34-year-old woman who developed acute fatty liver of pregnancy (AFLP) after delivery by caesarean section at 32 weeks of gestation. AFLP was complicated by acute pancreatitis and multiple organ failure. The management of the disease was primarily supportive. She recovered from acute fulminant liver failure and multi-organ failure, apart from the development of symptomatic chronic pancreatitis thereafter.

Results: Investigations failed to identify any other causes of chronic pancreatitis. The patient responded very well to pancreatic enzyme supplement for the treatment of steatorrhoea.

Conclusion: To our knowledge, this is the first report of chronic pancreatitis as a consequence of multi-organ dysfunction caused by AFLP.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Fatty Liver / complications*
  • Female
  • Humans
  • Liver Failure, Acute / complications*
  • Multiple Organ Failure / complications*
  • Pancreatitis, Chronic / diagnostic imaging
  • Pancreatitis, Chronic / etiology*
  • Pregnancy
  • Pregnancy Complications*
  • Tomography, X-Ray Computed