Osteoarticular infections in HIV-infected patients: 23 cases among 1,515 HIV-infected patients

Acta Orthop. 2007 Dec;78(6):786-90. doi: 10.1080/17453670710014554.

Abstract

Background: The reported incidence of osteoarticular infections in HIV-infected patients has varied in the literature. PATIENTS AND METHODS We determined the incidence and characteristics of osteoarticular infections reported in a database of 1,515 HIV-infected patients between 1983 and 2003.

Results: 23 HIV-infected patients were identified with an osteoarticular infection, 11 of whom had a spondylodiscitis. 16 were intravenous drug abusers; this was identified as a risk factor for developing an osteoarticular infection. The most common agent was Staphylococcus aureus. 6 patients required surgical intervention and in a worst-case scenario more than one-fifth had recurrence of their infection.

Conclusion: Development of an osteoarticular infection is a rare complication in this group of HIV-infected patients, but a remarkably high number of infections of the spine were seen.

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology*
  • AIDS-Related Opportunistic Infections / microbiology
  • AIDS-Related Opportunistic Infections / therapy
  • Adult
  • Bacterial Infections / epidemiology*
  • Bacterial Infections / microbiology
  • Bacterial Infections / therapy
  • Discitis / epidemiology
  • Discitis / microbiology
  • Discitis / therapy
  • Follow-Up Studies
  • HIV Infections / complications
  • HIV Infections / microbiology*
  • Humans
  • Incidence
  • Middle Aged
  • Netherlands / epidemiology
  • Osteoarthritis / epidemiology*
  • Osteoarthritis / microbiology
  • Osteoarthritis / therapy
  • Retrospective Studies
  • Spondylitis / epidemiology*
  • Spondylitis / microbiology
  • Spondylitis / therapy
  • Substance Abuse, Intravenous