Role of echocardiography in the diagnosis and management of asymptomatic severe aortic stenosis

Expert Rev Cardiovasc Ther. 2008 Feb;6(2):223-33. doi: 10.1586/14779072.6.2.223.

Abstract

Calcification of normal tricuspid and congenital bicuspid valves is the most common cause of aortic stenosis in industrialized countries. There is compelling evidence that thickening and calcification in aortic valve disease is a complex inflammatory process and not simply age-related degeneration. Both aortic sclerosis and stenosis represent phenotypic expressions of one disease continuum. Patients with symptomatic severe aortic stenosis benefit from aortic valve replacement. However, management in the absence of symptoms remains challenging. While a delay of aortic valve replacement due to lack of symptom recognition may result in a dismal outcome, unselected premature aortic valve replacement may be associated with unbalanced risks of cardiac surgery. Echocardiography is the standard for evaluating the severity of aortic stenosis; however, most of the current echocardiographic parameters have limitations in predicting the onset of symptoms. This review summarizes the current guidelines and the emerging application of echocardiographic techniques in the management of asymptomatic severe aortic stenosis.

Publication types

  • Review

MeSH terms

  • Aorta / pathology
  • Aortic Valve Stenosis / diagnostic imaging*
  • Aortic Valve Stenosis / etiology
  • Aortic Valve Stenosis / physiopathology
  • Aortic Valve Stenosis / therapy*
  • Echocardiography* / methods
  • Guidelines as Topic
  • Humans
  • Risk Factors
  • Sclerosis
  • Severity of Illness Index