Hyper-reactive malarial splenomegaly in a patient with human immunodeficiency virus

G De Iaco; N Saleri; F Perandin; M Gulletta; G Ravizzola; N Manca; L Signorini; A Matteelli; K Prestini; F Castelli

Hyper-reactive malarial splenomegaly in a patient with human immunodeficiency virus

Am J Trop Med Hyg. 2008 Feb;78(2):239-40.

Authors

G De Iaco¹, N Saleri, F Perandin, M Gulletta, G Ravizzola, N Manca, L Signorini, A Matteelli, K Prestini, F Castelli

Affiliation

¹ Infectious and Tropical Medicine Institute, University of Brescia, Italy.

PMID: 18256422

Abstract

Both hyperreactive malarial splenomegaly (HMS) and HIV infection are highly prevalent in sub-Saharan Africa, but the inter-relationships between the two conditions are not clearly defined. Diagnosis of HMS is particularly difficult in HIV-infected patients, and detection of circulating malaria parasites by polymerase chain reaction (PCR) may represent a useful diagnostic tool.

Publication types

Case Reports

MeSH terms

Animals
Anti-HIV Agents / therapeutic use
Antibodies, Protozoan / blood
Antimalarials / therapeutic use
Cameroon / ethnology
Diagnosis, Differential
Female
HIV / isolation & purification
HIV Infections / complications*
HIV Infections / diagnosis
Humans
Italy
Malaria / complications*
Malaria / diagnosis*
Mefloquine / therapeutic use
Middle Aged
Plasmodium falciparum / genetics
Plasmodium falciparum / isolation & purification*
Polymerase Chain Reaction
RNA, Ribosomal, 18S / genetics
Splenomegaly / diagnosis
Splenomegaly / etiology*

Substances

Anti-HIV Agents
Antibodies, Protozoan
Antimalarials
RNA, Ribosomal, 18S
Mefloquine