Abstract
We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum-infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Animals
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Antimalarials / administration & dosage
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Antimalarials / therapeutic use*
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Atovaquone* / administration & dosage
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Atovaquone* / therapeutic use
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Drug Therapy, Combination
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Humans
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Malaria, Falciparum / drug therapy*
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Malaria, Falciparum / parasitology
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Male
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Plasmodium falciparum / drug effects
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Proguanil* / administration & dosage
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Proguanil* / therapeutic use
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Treatment Failure
Substances
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Antimalarials
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Proguanil
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Atovaquone