Routine continuous cold perfusion of the kidneys during elective juxtarenal aortic aneurysm repair

Eur J Vasc Endovasc Surg. 2008 Apr;35(4):446-51. doi: 10.1016/j.ejvs.2007.11.022. Epub 2008 Feb 8.

Abstract

Objectives: Surgical treatment of JAAs (juxtarenal aortic aneurysms) requires suprarenal aortic cross-clamping, causing temporary renal artery occlusion. We implemented a standardized protocol of hypothermic renal perfusion for all elective JAA operations.

Design: Retrospective study.

Materials and methods: Over a period of 6 years, 23 consecutive patients received a 300ml bolus followed by an infusion (20ml/minute) of cold (4 degrees C) saline to each kidney during suprarenal aortic clamping. We assessed outcome in terms of rise in serum creatinine, new onset of dialysis and mortality.

Results: None of the patients suffered from postoperative acute renal failure and in-hospital mortality was zero. Five patients did not show any rise in serum creatinine level, whereas in the others rises were <25% in comparison with the admission level, except for one patient (38%). Postoperative rise in serum creatinine level was not related to renal ischemia time (Spearman rank correlation=0.24, p=0.27), preoperative renal function, total aortic clamping time or renal re-implantation. There were no renal complications at 6 months.

Conclusions: Our results suggest that a standardized strategy to apply renal hypothermia during the ischemic period of elective JAA surgery may reduce postoperative renal failure.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aortic Aneurysm, Abdominal / surgery*
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Blood Vessel Prosthesis Implantation / methods*
  • Cohort Studies
  • Female
  • Humans
  • Hypothermia, Induced*
  • Male
  • Middle Aged
  • Renal Artery*
  • Renal Insufficiency / etiology
  • Renal Insufficiency / prevention & control
  • Retrospective Studies
  • Stents