Mammalian limbs take flight

Dev Cell. 2008 Feb;14(2):149-50. doi: 10.1016/j.devcel.2008.01.011.

Abstract

Tetrapod limbs display a great variety of forms and functions. In an attempt to understand factors influencing this diversity, Cretekos and colleagues, in a recent issue of Genes & Development, provide molecular insight into the evolution of wing morphology in bats.

MeSH terms

  • Animals
  • Biological Evolution*
  • Chiroptera / anatomy & histology
  • Extremities / anatomy & histology*
  • Flight, Animal*
  • Forelimb / anatomy & histology
  • Gene Expression Regulation
  • Homeodomain Proteins / genetics
  • Mammals / anatomy & histology*
  • Mice
  • Regulatory Sequences, Nucleic Acid

Substances

  • Homeodomain Proteins
  • Prrx1 protein, mouse