Fas Bim boom!

Immunity. 2008 Feb;28(2):141-3. doi: 10.1016/j.immuni.2008.01.004.

Abstract

New findings by Hughes et al. (2008), Hutcheson et al. (2008), and Weant et al. (2008) highlight the roles of apoptosis regulators Bim and Fas in the contraction phase of T cell responses and reveal consequences of failure of this process.

Publication types

  • Comment

MeSH terms

  • Animals
  • Apoptosis Regulatory Proteins / immunology
  • Apoptosis Regulatory Proteins / metabolism*
  • Apoptosis*
  • Bcl-2-Like Protein 11
  • Fas Ligand Protein / immunology
  • Fas Ligand Protein / metabolism
  • Humans
  • Lymphocyte Activation
  • Membrane Proteins / metabolism*
  • Mice
  • Proto-Oncogene Proteins / metabolism*
  • T-Lymphocyte Subsets / immunology*
  • T-Lymphocyte Subsets / physiology
  • fas Receptor / immunology
  • fas Receptor / metabolism*

Substances

  • Apoptosis Regulatory Proteins
  • BCL2L11 protein, human
  • Bcl-2-Like Protein 11
  • Bcl2l11 protein, mouse
  • Fas Ligand Protein
  • Membrane Proteins
  • Proto-Oncogene Proteins
  • fas Receptor