Prevalence of virulence genes and cytolethal distending toxin production in Campylobacter jejuni isolates from diarrheal patients in Bangladesh

J Clin Microbiol. 2008 Apr;46(4):1485-8. doi: 10.1128/JCM.01912-07. Epub 2008 Feb 20.

Abstract

From 300 stool samples, 58 Campylobacter strains were isolated by standard microbiological and biochemical methods. Of these, 40 strains were identified as Campylobacter jejuni and 5 as Campylobacter coli. The presence of flaA (100%), cadF (100%), racR (100%), dnaJ (100%), pldA (100%), ciaB (95%), virB11 (0%), ceuE (82.5%), cdtA (97.5%), cdtB (97.5%), cdtC (97.5%), and wlaN (7.5%) genes was detected in C. jejuni by PCR. All C. jejuni strains but one produced cytolethal distending toxin in a HeLa cell assay.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Toxins / biosynthesis*
  • Bacterial Toxins / genetics
  • Bacterial Toxins / toxicity
  • Bangladesh / epidemiology
  • Campylobacter Infections* / epidemiology
  • Campylobacter Infections* / microbiology
  • Campylobacter coli / classification
  • Campylobacter coli / genetics
  • Campylobacter coli / isolation & purification
  • Campylobacter coli / pathogenicity
  • Campylobacter jejuni* / classification
  • Campylobacter jejuni* / genetics
  • Campylobacter jejuni* / isolation & purification
  • Campylobacter jejuni* / pathogenicity
  • Diarrhea* / epidemiology
  • Diarrhea* / microbiology
  • Feces / microbiology
  • HeLa Cells
  • Humans
  • Polymerase Chain Reaction / methods
  • Prevalence
  • Virulence / genetics
  • Virulence Factors / genetics*

Substances

  • Bacterial Proteins
  • Bacterial Toxins
  • Virulence Factors
  • cytolethal distending toxin