Localization of the TRK proto-oncogene to human chromosome bands 1q23-1q24

Oncogene. 1991 Jun;6(6):1093-5.

Abstract

A FER-related sequence isolated from a human genomic library was found to be homologous to TRK. In situ hybridization of a 0.92 kb probe, isolated from this sequence, localized the TRK gene to the long arm of chromosome 1 within bands 1q23-1q24. This is a significantly more proximal location of TRK than the 1q32-1q41 site published recently (Miozzo et al., 1990).

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Chromosome Mapping*
  • Chromosomes, Human, Pair 1*
  • DNA Probes
  • Humans
  • Molecular Sequence Data
  • Oncogene Proteins / genetics*
  • Proto-Oncogene Mas

Substances

  • DNA Probes
  • MAS1 protein, human
  • Oncogene Proteins
  • Proto-Oncogene Mas
  • oncogene protein trk