Abstract
A novel 2,3-dioxygenated flavanone, erigeroflavanone ( 1), as well as eight known flavonoids and two known gamma-pyranone derivatives, were isolated from an ethyl acetate-soluble extract of the flowers of Erigeron annuus. The structure of compound 1 was elucidated by interpretation of spectroscopic data. All of the isolates were subjected to in vitro bioassays to evaluate their inhibitory activity against advanced glycation end products formation and rat lens aldose reductase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehyde Reductase / antagonists & inhibitors*
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Animals
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Erigeron / chemistry*
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Flavanones / chemistry
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Flavanones / isolation & purification*
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Flavanones / pharmacology*
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Flowers / chemistry
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Glycation End Products, Advanced / antagonists & inhibitors*
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Korea
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Lens, Crystalline / enzymology
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Molecular Structure
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Plants, Medicinal / chemistry*
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Rats
Substances
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Flavanones
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Glycation End Products, Advanced
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erigeroflavanone
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Aldehyde Reductase