Appendicitis in immunosuppressed children: Still a diagnostic and therapeutic dilemma?

Pediatr Blood Cancer. 2008 Jun;50(6):1282-3. doi: 10.1002/pbc.21554.

Abstract

Acute appendicitis in the immunosuppressed patients are often difficult to diagnose and are associated with increased morbidity and mortality. Recent debates on primary appendicitis and typhlitis-associated appendicitis have contributed to the diagnostic and therapeutic dilemma. We retrospectively reviewed all our immunosuppressed patients with appendicitis. The most frequent presenting symptom was fever followed by non-specific intermittent abdominal pain. The median delay in diagnosis was 4 days. CT scan was useful in making the diagnosis, but the presence of adjacent bowel thickening has contributed to the dilemma in diagnosis and treatment.

MeSH terms

  • Adolescent
  • Appendectomy
  • Appendicitis / diagnosis*
  • Appendicitis / surgery
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunosuppression Therapy*
  • Male