Acute dystonic reaction in an adolescent on risperidone when a concomitant stimulant medication is discontinued

J Child Adolesc Psychopharmacol. 2007 Dec;17(6):867-70. doi: 10.1089/cap.2007.0047.

Abstract

This report describes an acute dystonic reaction that occurred after dexamphetamine was discontinued from a drug regimen that included risperidone. This is the second report that has revealed a possible rebound dystonia when a stimulant medication is withdrawn from a patient taking risperidone. We also discuss the neurophysiological hypotheses and implications for treatment.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antipsychotic Agents / adverse effects*
  • Attention Deficit Disorder with Hyperactivity / drug therapy
  • Central Nervous System Stimulants / administration & dosage
  • Dextroamphetamine / administration & dosage
  • Drug Administration Schedule
  • Dystonia / chemically induced*
  • Humans
  • Male
  • Risperidone / adverse effects*

Substances

  • Antipsychotic Agents
  • Central Nervous System Stimulants
  • Risperidone
  • Dextroamphetamine