Spontaneous resolution of vitreomacular traction following ranibizumab (Lucentis) injection

Eur J Ophthalmol. 2008 Mar-Apr;18(2):301-3. doi: 10.1177/112067210801800223.

Abstract

Purpose: Spontaneous resolution of vitreomacular traction syndrome in diabetic patients is a rare phenomenon that has been poorly described in the literature.

Methods: Case presentation.

Results: The authors present a case of spontaneous resolution of vitreomacular traction following intravitreal administration of ranibizumab.

Conclusions: In patients with vitreomacular traction syndrome and diabetic macular edema, the combination of the possible vitreous liquefaction and mechanical increase of vitreous volume caused by an intravitreal injection with a degree of reduction in retinal thickness caused by the effect of vascular endothelial growth factor inhibition could play a role in the resolution of vitreomacular traction.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angiogenesis Inhibitors / administration & dosage*
  • Antibodies, Monoclonal / administration & dosage*
  • Antibodies, Monoclonal, Humanized
  • Diabetic Retinopathy / complications
  • Eye Diseases / diagnosis
  • Eye Diseases / drug therapy*
  • Fluorescein Angiography
  • Humans
  • Injections
  • Macular Edema / diagnosis
  • Macular Edema / drug therapy
  • Macular Edema / etiology
  • Male
  • Ranibizumab
  • Remission, Spontaneous
  • Retinal Diseases / diagnosis
  • Retinal Diseases / drug therapy*
  • Syndrome
  • Tissue Adhesions / diagnosis
  • Tissue Adhesions / drug therapy
  • Tomography, Optical Coherence
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors
  • Vitreous Body / drug effects*
  • Vitreous Body / pathology

Substances

  • Angiogenesis Inhibitors
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Vascular Endothelial Growth Factor A
  • Ranibizumab