Test-retest reliability of the Urge-Urinary Distress Inventory (U-UDI) and the Female Sexual Function Index (FSFI) was assessed in women with multiple sclerosis (MS) because it was undetermined whether or not either instrument would yield reliable and valid results in this population. Data from this study suggest that these tools can be reliably used to assess community-dwelling women with mild gait disability and MS-associated symptoms of urinary distress and sexual dysfunction.