Rapid interactions between the ventral visual stream and emotion-related structures rely on a two-pathway architecture

J Neurosci. 2008 Mar 12;28(11):2793-803. doi: 10.1523/JNEUROSCI.3476-07.2008.

Abstract

Visual attention can be driven by the affective significance of visual stimuli before full-fledged processing of the stimuli. Two kinds of models have been proposed to explain this phenomenon: models involving sequential processing along the ventral visual stream, with secondary feedback from emotion-related structures ("two-stage models"); and models including additional short-cut pathways directly reaching the emotion-related structures ("two-pathway models"). We tested which type of model would best predict real magnetoencephalographic responses in subjects presented with arousing visual stimuli, using realistic models of large-scale cerebral architecture and neural biophysics. The results strongly support a "two-pathway" hypothesis. Both standard models including the retinotectal pathway and nonstandard models including cortical-cortical long-range fasciculi appear plausible.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Emotions / physiology*
  • Humans
  • Magnetoencephalography / methods
  • Male
  • Middle Aged
  • Nerve Net / physiology
  • Photic Stimulation / methods*
  • Time Factors
  • Visual Cortex / physiology
  • Visual Pathways / physiology*
  • Visual Perception / physiology*