Abstract
Polysubstituted benzene derivatives with an unprecedented substitution pattern are produced in a novel one-pot multi-component cyclization reaction from pyridine, ethyl alpha-bromoacetate, malononitrile and aromatic aldehyde in refluxing acetonitrile.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Acetates / chemistry*
-
Aldehydes / chemistry*
-
Benzene Derivatives / chemical synthesis*
-
Benzene Derivatives / chemistry
-
Crystallography, X-Ray
-
Cyclization
-
Models, Molecular
-
Molecular Structure
-
Nitriles / chemistry*
-
Stereoisomerism
Substances
-
Acetates
-
Aldehydes
-
Benzene Derivatives
-
Nitriles
-
bromoacetate
-
dicyanmethane