Infectious arthritis as the single manifestation of sporotrichosis: serology from serum and synovial fluid samples as an aid to diagnosis

Rev Iberoam Micol. 2008 Mar;25(1):54-6. doi: 10.1016/s1130-1406(08)70014-7.

Abstract

Sporotrichosis is a generally cutaneous, granulomatous, chronic and benign infection. Less frequently the disease may affect the joints. Articular involvement is usually characterized by monoarthritis in the absence of systemic symptoms, generally preceded by skin lesions, and frequently affects immunosuppressed individuals. We describe here the case of a healthy patient presenting knee arthritis without skin lesions, diagnosed as sporotrichosis, and treated with oral itraconazole. Serology used in this case was an invaluable tool for the diagnosis of sporotrichosis arthritis lacking skin lesions.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Antibodies, Fungal / analysis*
  • Antifungal Agents / therapeutic use
  • Arthritis, Infectious / blood
  • Arthritis, Infectious / diagnosis*
  • Arthritis, Infectious / drug therapy
  • Arthritis, Infectious / microbiology
  • Arthroscopy
  • Biopsy
  • Female
  • Humans
  • Itraconazole / therapeutic use
  • Knee Joint / microbiology*
  • Sporothrix / immunology
  • Sporothrix / isolation & purification*
  • Sporotrichosis / blood
  • Sporotrichosis / diagnosis*
  • Sporotrichosis / drug therapy
  • Synovial Fluid / immunology
  • Synovial Fluid / microbiology

Substances

  • Antibodies, Fungal
  • Antifungal Agents
  • Itraconazole