Acute dystonia induced by the combination of midodrine and perphenazine

J Neurol. 2008 May;255(5):767-8. doi: 10.1007/s00415-008-0805-y. Epub 2008 Mar 17.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Acute Disease
  • Adrenergic alpha-1 Receptor Agonists
  • Antipsychotic Agents / adverse effects
  • Cytochrome P-450 CYP2D6 / metabolism
  • Cytochrome P-450 CYP2D6 Inhibitors
  • Depressive Disorder, Major / drug therapy
  • Drug Interactions / physiology
  • Drug Therapy, Combination
  • Dyskinesia, Drug-Induced / physiopathology*
  • Dystonia / chemically induced*
  • Dystonia / physiopathology*
  • Female
  • Humans
  • Hypotension, Orthostatic / chemically induced
  • Hypotension, Orthostatic / drug therapy
  • Middle Aged
  • Midodrine / adverse effects*
  • Perphenazine / adverse effects*
  • Receptors, Adrenergic, alpha-1 / metabolism
  • Vasoconstrictor Agents / adverse effects

Substances

  • Adrenergic alpha-1 Receptor Agonists
  • Antipsychotic Agents
  • Cytochrome P-450 CYP2D6 Inhibitors
  • Receptors, Adrenergic, alpha-1
  • Vasoconstrictor Agents
  • Midodrine
  • Cytochrome P-450 CYP2D6
  • Perphenazine