Weekly long-term intravenous immunoglobulin for refractory parvovirus B19 and Epstein-Barr virus-induced immune thrombocytopenic purpura

Turk J Pediatr. 2008 Jan-Feb;50(1):74-7.

Abstract

In pediatric acute immune thrombocytopenic purpura (ITP) cases, it is usually possible to determine an underlying pathology; among them, viral infections are the leading causative agents. In this report, we describe two cases of acute ITP complicated secondary to parvovirus B19 or Epstein-Barr virus (EBV) infections who were unresponsive to initial therapeutic measures, but who responded to long-term intravenous immunoglobulin (IVIG) treatment, given weekly for five to eight weeks.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Child, Preschool
  • Epstein-Barr Virus Infections / complications*
  • Humans
  • Immunoglobulins, Intravenous / administration & dosage*
  • Immunologic Factors / administration & dosage*
  • Male
  • Parvoviridae Infections / complications*
  • Parvovirus B19, Human*
  • Purpura, Thrombocytopenic, Idiopathic / diagnosis
  • Purpura, Thrombocytopenic, Idiopathic / drug therapy*
  • Purpura, Thrombocytopenic, Idiopathic / virology*

Substances

  • Immunoglobulins, Intravenous
  • Immunologic Factors