MtDNA mutation associated with mitochondrial dysfunction in megakaryoblastic leukaemic cells

Leukemia. 2008 Oct;22(10):1938-41. doi: 10.1038/leu.2008.69. Epub 2008 Mar 27.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA, Mitochondrial / genetics*
  • Humans
  • Leukemia, Megakaryoblastic, Acute / genetics*
  • Leukemia, Megakaryoblastic, Acute / metabolism*
  • Mitochondria / metabolism*
  • Mutation*
  • NADH Dehydrogenase / genetics
  • Oxidative Phosphorylation
  • Oxygen Consumption
  • Reactive Oxygen Species / metabolism

Substances

  • DNA, Mitochondrial
  • Reactive Oxygen Species
  • NADH Dehydrogenase
  • NADH dehydrogenase subunit 1, human