Mitochondria, oxidative stress and PARP-1 network: a new target for neuroprotective effects of tetracyclines?

J Physiol. 2008 May 15;586(10):2427-8. doi: 10.1113/jphysiol.2008.152819. Epub 2008 Mar 27.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Delivery Systems / methods
  • Humans
  • Mitochondria / drug effects*
  • Mitochondria / metabolism
  • Neuroprotective Agents / pharmacology*
  • Oxidative Stress / drug effects*
  • Oxidative Stress / physiology
  • Poly (ADP-Ribose) Polymerase-1
  • Poly(ADP-ribose) Polymerases / metabolism*
  • Tetracyclines / pharmacology*
  • Tetracyclines / therapeutic use

Substances

  • Neuroprotective Agents
  • Tetracyclines
  • PARP1 protein, human
  • Poly (ADP-Ribose) Polymerase-1
  • Poly(ADP-ribose) Polymerases