When good cholesterol turns bad: the evolving saga of CETP inhibitors and clinical strategies to elevate high-density lipoprotein

Curr Atheroscler Rep. 2007 Dec;9(6):425-7. doi: 10.1007/s11883-007-0055-y.

Authors

John F Oram¹, Jay W Heinecke

Affiliation

¹ Department of Medicine, Box 356426, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195-6426, USA. [email protected]

PMID: 18377780
DOI: 10.1007/s11883-007-0055-y

No abstract available

MeSH terms

ATP Binding Cassette Transporter 1
ATP-Binding Cassette Transporters / genetics
Anticholesteremic Agents / pharmacology
Anticholesteremic Agents / therapeutic use
Atherosclerosis / blood
Atherosclerosis / prevention & control
Blood Pressure / drug effects
Cardiovascular Diseases / blood*
Cardiovascular Diseases / genetics
Cholesterol Ester Transfer Proteins / antagonists & inhibitors*
Cholesterol, HDL / blood*
Cholesterol, HDL / drug effects*
Cholesterol, LDL / blood*
Humans
Liver / metabolism
Quinolines / pharmacology
Quinolines / therapeutic use

Substances

ATP Binding Cassette Transporter 1
ATP-Binding Cassette Transporters
Anticholesteremic Agents
Cholesterol Ester Transfer Proteins
Cholesterol, HDL
Cholesterol, LDL
Quinolines
torcetrapib