To identify correlates of epilepsy development in patients after brain injury, the authors carried out a comparative assessment of the spatial organization of brain electrical activity in patients with consequences of closed craniocerebral injury without epilepsy (53 patients) and in patients with post-traumatic epilepsy (43 patients). A control group included 15 subjects. The EEG study with spectral coherent analysis allows to predict post-traumatic epilepsy and to use a differential approach in prescribing the appropriate anticonvulsive therapy to people after head injury.