Improving defences at the portal of HIV entry: mucosal and innate immunity

PLoS Med. 2008 Apr 1;5(4):e81. doi: 10.1371/journal.pmed.0050081.

Authors

Robin J Shattock¹, Barton F Haynes, Bali Pulendran, Jorge Flores, José Esparza; Working Group convened by the Global HIV Vaccine Enterprise

Collaborators

Working Group convened by the Global HIV Vaccine Enterprise:
Alan Aderem, Lesley Bergmeir, James Bradac, Jason Brenchley, Heather Davis, Tom Hope, Pamela Kozlowski, Roger Le Grand, Thomas Lehner, Norman Letvin, Jay Levy, John Mascola, Julie McElrath, Philip Norris, Jo-Ann Passmore, Helen Quill, Robert Seder, Rafick-Pierra Sekaly, Barbara Shacklett, Georgia Tomaras, Ronald Veazey, Peter Wright

Affiliation

¹ St George's, University of London, London, United Kingdom. [email protected]

Abstract

The authors discuss the key scientific issues in mucosal and innate immunity related to immune protection against HIV infection.

MeSH terms

AIDS Vaccines / immunology*
Dendritic Cells / immunology
HIV / immunology*
HIV Infections / immunology*
HIV Infections / prevention & control
HIV Infections / transmission
HIV Infections / virology
Humans
Immunity, Innate*
Immunity, Mucosal*
T-Lymphocytes / immunology
Toll-Like Receptors / immunology
Virus Internalization*

Substances

AIDS Vaccines
Toll-Like Receptors