Validation and standardization of the Generalized Anxiety Disorder Screener (GAD-7) in the general population

Med Care. 2008 Mar;46(3):266-74. doi: 10.1097/MLR.0b013e318160d093.

Abstract

Background: The 7-item Generalized Anxiety Disorder Scale (GAD-7) is a practical self-report anxiety questionnaire that proved valid in primary care. However, the GAD-7 was not yet validated in the general population and thus far, normative data are not available.

Objectives: To investigate reliability, construct validity, and factorial validity of the GAD-7 in the general population and to generate normative data.

Research design: Nationally representative face-to-face household survey conducted in Germany between May 5 and June 8, 2006.

Subjects: Five thousand thirty subjects (53.6% female) with a mean age (SD) of 48.4 (18.0) years.

Measures: The survey questionnaire included the GAD-7, the 2-item depression module from the Patient Health Questionnaire (PHQ-2), the Rosenberg Self-Esteem Scale, and demographic characteristics.

Results: Confirmatory factor analyses substantiated the 1-dimensional structure of the GAD-7 and its factorial invariance for gender and age. Internal consistency was identical across all subgroups (alpha = 0.89). Intercorrelations with the PHQ-2 and the Rosenberg Self-Esteem Scale were r = 0.64 (P < 0.001) and r = -0.43 (P < 0.001), respectively. As expected, women had significantly higher mean (SD) GAD-7 anxiety scores compared with men [3.2 (3.5) vs. 2.7 (3.2); P < 0.001]. Normative data for the GAD-7 were generated for both genders and different age levels. Approximately 5% of subjects had GAD-7 scores of 10 or greater, and 1% had GAD-7 scores of 15 or greater.

Conclusions: Evidence supports reliability and validity of the GAD-7 as a measure of anxiety in the general population. The normative data provided in this study can be used to compare a subject's GAD-7 score with those determined from a general population reference group.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anxiety Disorders / diagnosis*
  • Female
  • Humans
  • Male
  • Mass Screening / methods*
  • Middle Aged
  • Primary Health Care
  • Psychometrics / methods
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Socioeconomic Factors
  • Surveys and Questionnaires*