Abstract
The genetic environment of the 16S rRNA methylase gene rmtD was investigated. rmtD was flanked by a novel ISCR motif located downstream of class I integron In163 in the original Pseudomonas aeruginosa strain. rmtD found in Klebsiella pneumoniae appeared to have been mobilized from P. aeruginosa by an IS26-mediated event.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Aminoglycosides / pharmacology
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Anti-Bacterial Agents / pharmacology
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Bacterial Proteins / chemistry
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Bacterial Proteins / genetics
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DNA Transposable Elements*
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Drug Resistance, Bacterial / genetics
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Genes, rRNA
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Integrons / genetics
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Klebsiella pneumoniae / drug effects
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Klebsiella pneumoniae / enzymology
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Klebsiella pneumoniae / genetics*
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Methyltransferases / genetics*
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Molecular Sequence Data
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Pseudomonas aeruginosa / drug effects
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Pseudomonas aeruginosa / enzymology
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Pseudomonas aeruginosa / genetics*
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RNA, Ribosomal, 16S / genetics*
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Recombination, Genetic
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Sequence Analysis, DNA
Substances
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Aminoglycosides
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Anti-Bacterial Agents
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Bacterial Proteins
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DNA Transposable Elements
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RNA, Ribosomal, 16S
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Methyltransferases
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rRNA (adenosine-O-2'-)methyltransferase
Associated data
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GENBANK/DQ914960
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GENBANK/EU269034