Illuminating the black box of reprogramming

Rupa Sridharan; Kathrin Plath

doi:10.1016/j.stem.2008.03.015

Illuminating the black box of reprogramming

Cell Stem Cell. 2008 Apr 10;2(4):295-7. doi: 10.1016/j.stem.2008.03.015.

Authors

Rupa Sridharan¹, Kathrin Plath

Affiliation

¹ Department of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.

PMID: 18397745
DOI: 10.1016/j.stem.2008.03.015

Abstract

Yamanaka and colleagues, in a Science article currently published online, have generated induced pluripotent stem (iPS) cells from liver and stomach cells, suggesting that transcription factor-induced reprogramming is not restricted to particular cell types (Aoi et al., 2008). These results also provide important insight into the mechanistic basis of reprogramming.

Publication types

Editorial

MeSH terms

Animals
Cell Nucleus / physiology*
Cellular Reprogramming*
Embryo, Mammalian / cytology
Embryo, Mammalian / physiology*
Humans
Pluripotent Stem Cells / cytology*
Transcription Factors / metabolism*

Substances

Transcription Factors