[The surgical treatment of renal cell carcinoma metastases to the vertebrae: intra-operative anesthesia related problems]

Clin Ter. 2008 Jan-Feb;159(1):23-8.
[Article in Italian]

Abstract

Aims: Analysis of the intra-operative anesthesia related problems were compared during intra-lesional or extra-lesional surgeries for patients with metastatic renal cell carcinoma to the spine.

Materials and methods: We retrospectively collected and analyzed the hemodynamic data on 30 patients who had undergone surgical intervention. Twenty patients had an intra-lesional excision of the metastatic lesion in the vertebra, whereas for the rest, an en-bloc wide or marginal margin resection was carried out.

Results: The surgical time for the en-bloc resections was much longer, and thus also the exposure to the anesthesia, but lesser variability within the data on blood pressure and pulse as compared with intra-lesional curettage. There was also more blood loss with the intra-lesional surgeries.

Conclusions: En-bloc resections of the vertebral tumors not only give better oncological local control, but also have less compromising effects on the patient, especially with respect to the intra-operative hemodynamics. In selected cases, en-bloc resections present a good option of treatment in vertebral metastases, and especially in highly vascular tumors such as the renal cell carcinoma metastases.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anesthesia / adverse effects*
  • Anesthesia / methods
  • Carcinoma, Renal Cell / secondary
  • Carcinoma, Renal Cell / surgery*
  • Debridement / methods
  • Female
  • Humans
  • Intraoperative Period
  • Kidney Neoplasms / pathology*
  • Lumbar Vertebrae / surgery*
  • Male
  • Middle Aged
  • Neurosurgical Procedures / methods
  • Retrospective Studies
  • Spinal Neoplasms / secondary
  • Spinal Neoplasms / surgery*
  • Thoracic Vertebrae / surgery*
  • Treatment Outcome