Azadipeptide nitriles: highly potent and proteolytically stable inhibitors of papain-like cysteine proteases

Angew Chem Int Ed Engl. 2008;47(23):4331-4. doi: 10.1002/anie.200705858.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aza Compounds / chemical synthesis
  • Aza Compounds / chemistry*
  • Aza Compounds / pharmacology
  • Cysteine Proteinase Inhibitors / chemical synthesis
  • Cysteine Proteinase Inhibitors / chemistry*
  • Cysteine Proteinase Inhibitors / pharmacology
  • Dipeptides / chemical synthesis
  • Dipeptides / chemistry*
  • Dipeptides / pharmacology
  • Humans
  • Nitriles / chemical synthesis
  • Nitriles / chemistry*
  • Nitriles / pharmacology
  • Papain / antagonists & inhibitors*

Substances

  • Aza Compounds
  • Cysteine Proteinase Inhibitors
  • Dipeptides
  • Nitriles
  • Papain